PPP011 - QT prolongation with Dr Dawson MacLeod

PPP011 - QT prolongation with Dr Dawson MacLeod

 Image by GiggsHammouri, used under a creative commons license from Wikimedia

Image by GiggsHammouri, used under a creative commons license from Wikimedia

Jane is joined by Dawson MacLeod, a specialist in poisons information from the Victorian Poisons Information Centre.

Jane talks to Dawson about:

·      The cardiac QT interval and its clinical significance

·      Risk factors for QT prolongation, particularly in the context of drug interactions

·      The best way to monitor and calculate a corrected QT interval from an ECG

·      Medicines of greatest concern for QT prolongation

Further reading:

·      Therapeutic Guidelines: Toxicology and Wilderness Figure 17.1: QT interval nomogram to assess risk of drug-induced torsades de pointes

·      CredibleMeds® QTdrugs lists

·      Isbister GK. Risk assessment of drug-induced QT prolongation Aust Prescr: 2015;38:20-4

·      Rotella JA et al. Accuracy of QT interval measurement on electrocardiographs displayed on electronic 'smart' devices. Emerg Med Australas. 2016 Apr;28(2):187-92

PPP012 - Biosimilars with Dr David Liew

PPP012 - Biosimilars with Dr David Liew

PPP010 - Michael Ward - Drug interactions and pharmacogenomics

PPP010 - Michael Ward - Drug interactions and pharmacogenomics